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Unchangeable features associated with higher pancreatic cancer risk include: being assigned male at birth having a Helicobacter pylori infection being over the age of 45 years having a relative diagnosed with pancreatic cancer being African American living with certain inherited genetic syndromes chronic gene-related pancreatitis A limited number of studies have shown that alcohol consumption, poor diet, and physical inactivity may also contribute to pancreatic cancer risk, but more research in these areas is needed